Cellosaurus cell line MLEC-Hs6st1-/-;Hs6st2-/- (CVCL

Cross-references
Cell line name	MLEC-Hs6st1-/-;Hs6st2-/-
Synonyms	Mouse Lung Endothelial Hs6st1-/-;Hs6st2-/-
Accession	CVCL_ZD25
Resource Identification Initiative	To cite this cell line use: MLEC-Hs6st1-/-;Hs6st2-/- (RRID:CVCL_ZD25)
Comments	Knockout cell: Method=Floxing/Cre recombination; MGI; MGI:1354958; Hs6st1. Knockout cell: Method=KO mouse; MGI; MGI:1354959; Hs6st2. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Lung; UBERON=UBERON_0002048. Cell type: Endothelial cell of lung; CL=CL_1001567. Breed/subspecies: Hs2st1f/f;Hs6st2-/- x C57BL/6J.
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy	Parent: CVCL_ZD23 (MLEC-Hs6st1f/f;Hs6st2-/-)
Sex of cell	Sex unspecified
Age at sampling	8-10W
Category	Transformed cell line
Publications	PubMed=30377379; DOI=10.1038/s41592-018-0189-6; PMCID=PMC6214364 Qiu H., Shi S.-S., Yue J.-W., Xin M., Nairn A.V., Lin L., Liu X., Li G., Archer-Hartmann S.A., Dela Rosa M., Galizzi M., Wang S.-C., Zhang F., Azadi P., van Kuppevelt T.H., Cardoso W.V., Kimata K., Ai X.-B., Moremen K.W., Esko J.D., Linhardt R.J., Wang L.-C. A mutant-cell library for systematic analysis of heparan sulfate structure-function relationships. Nat. Methods 15:889-899(2018)
Cell line collections (Providers)	Kerafast; EGA366
Encyclopedic resources	Wikidata; Q98127261
Entry history
Entry creation	02-Jul-2020
Last entry update	10-Sep-2024
Version number	8