ID   Mel 93.03
AC   CVCL_ZD09
SY   93.03
DR   cancercelllines; CVCL_ZD09
DR   Wikidata; Q98127218
RX   PubMed=23685455;
RX   PubMed=25538140;
CC   From: Leiden University Medical Center; Leiden; Netherlands.
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=23685455; PubMed=25538140).
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
CA   Cancer cell line
DT   Created: 02-07-20; Last updated: 19-12-24; Version: 6
//
RX   PubMed=23685455; DOI=10.1038/nature12154;
RA   Kaplon J., Zheng L., Meissl K., Chaneton B., Selivanov V.A.,
RA   Mackay G., van der Burg S.H., Verdegaal E.M.E., Cascante M., Shlomi T.,
RA   Gottlieb E., Peeper D.S.;
RT   "A key role for mitochondrial gatekeeper pyruvate dehydrogenase in
RT   oncogene-induced senescence.";
RL   Nature 498:109-112(2013).
//
RX   PubMed=25538140; DOI=10.15252/msb.20145450; PMCID=PMC4300494;
RA   Smit M.A., Maddalo G., Greig K., Raaijmakers L.M., Possik P.A.,
RA   van Breukelen B., Cappadona S., Heck A.J.R., Altelaar A.F.M.,
RA   Peeper D.S.;
RT   "ROCK1 is a potential combinatorial drug target for BRAF mutant
RT   melanoma.";
RL   Mol. Syst. Biol. 10:772-772(2014).
//