Cellosaurus cell line Mel 04.07 (CVCL

Cross-references
Cell line name	Mel 04.07
Synonyms	04.07
Accession	CVCL_ZD08
Resource Identification Initiative	To cite this cell line use: Mel 04.07 (RRID:CVCL_ZD08)
Comments	From: Leiden University Medical Center; Leiden; Netherlands.
Sequence variations	Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=23685455; PubMed=25538140).
Disease	Melanoma (NCIt: C3224)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category	Cancer cell line
Publications	PubMed=23685455; DOI=10.1038/nature12154 Kaplon J., Zheng L., Meissl K., Chaneton B., Selivanov V.A., Mackay G., van der Burg S.H., Verdegaal E.M.E., Cascante M., Shlomi T., Gottlieb E., Peeper D.S. A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence. Nature 498:109-112(2013) PubMed=25538140; DOI=10.15252/msb.20145450; PMCID=PMC4300494 Smit M.A., Maddalo G., Greig K., Raaijmakers L.M., Possik P.A., van Breukelen B., Cappadona S., Heck A.J.R., Altelaar A.F.M., Peeper D.S. ROCK1 is a potential combinatorial drug target for BRAF mutant melanoma. Mol. Syst. Biol. 10:772-772(2014)
Cell line databases/resources	cancercelllines; CVCL_ZD08
Encyclopedic resources	Wikidata; Q98127210
Entry history
Entry creation	02-Jul-2020
Last entry update	19-Dec-2024
Version number	6