Cellosaurus cell line UNCCF2T (CVCL

Cellosaurus UNCCF2T (CVCL_ZC89)

[Text version]

Cell line name

UNCCF2T

Accession

CVCL_ZC89

Resource Identification Initiative

To cite this cell line use: UNCCF2T (RRID:CVCL_ZC89)

Comments

Population: Caucasian.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=MGI; MGI:88174; Bmi1.
Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
Cell type: Epithelial cell of bronchus; CL=CL_0002328.

Sequence variations

Mutation; HGNC; HGNC:1884; CFTR; Simple; p.Phe508del (c.1521_1523delCTT); ClinVar=VCV000007105; Zygosity=Homozygous (PubMed=18978040).

Disease

Cystic fibrosis (NCIt: C2975)
Cystic fibrosis (ORDO: Orphanet_586)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

18Y

Category

Telomerase immortalized cell line

STR profile

Source(s): PubMed=18978040

Markers:

Amelogenin	X
CSF1PO	10
D5S818	13,14
D7S820	9,10
D13S317	11
D16S539	11,12
TH01	6,7
TPOX	8,11
vWA	17,19

Publications

PubMed=18978040; DOI=10.1152/ajplung.90314.2008; PMCID=PMC2636952
Fulcher M.L., Gabriel S.E., Olsen J.C., Tatreau J.R., Gentzsch M., Livanos-Gonzalez E., Saavedra M.T., Salmon P., Randell S.H.
Novel human bronchial epithelial cell lines for cystic fibrosis research.
Am. J. Physiol. Lung Cell. Mol. Physiol. 296:L82-L91(2009)

Cross-references

Cell line collections (Providers)

Kerafast; ENC015 - Discontinued

Encyclopedic resources

Wikidata; Q98134237

Entry history

Entry creation

02-Jul-2020

Last entry update

19-Dec-2024

Version number