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Cellosaurus FRDA4627 (CVCL_ZC03)

[Text version]
Cell line name FRDA4627
Synonyms F4627; 4627
Accession CVCL_ZC03
Resource Identification Initiative To cite this cell line use: FRDA4627 (RRID:CVCL_ZC03)
Comments Part of: Friedreich's ataxia primary fibroblast repository.
Omics: Transcriptomics; RNAseq.
Caution: According to PubMed=29125828, the number of GAA repeats are 468/807.
Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
Disease Friedreich ataxia (NCIt: C84718)
Friedreich ataxia (ORDO: Orphanet_95)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 50Y
Category Finite cell line
Publications

PubMed=29125828; DOI=10.1242/dmm.030536; PMCID=PMC5719256
Napierala J.S., Li Y.-J., Lu Y., Lin K., Hauser L.A., Lynch D.R., Napierala M.
Comprehensive analysis of gene expression patterns in Friedreich's ataxia fibroblasts by RNA sequencing reveals altered levels of protein synthesis factors and solute carriers.
Dis. Model. Mech. 10:1353-1369(2017)

PubMed=32291635; DOI=10.1007/s12035-020-01899-1; PMCID=PMC7253519
Misiorek J.O., Schreiber A.M., Urbanek-Trzeciak M.O., Hauser L.A., Lynch D.R., Napierala J.S., Napierala M.
A comprehensive transcriptome analysis identifies FXN and BDNF as novel targets of miRNAs in Friedreich's ataxia patients.
Mol. Neurobiol. 57:2639-2653(2020)

Cross-references
Encyclopedic resources Wikidata; Q98126258
Gene expression databases GEO; GSM2794430
Entry history
Entry creation02-Jul-2020
Last entry update10-Apr-2025
Version number9