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Cellosaurus FRDA281 (CVCL_ZB93)

[Text version]
Cell line name FRDA281
Synonyms F281; 281
Accession CVCL_ZB93
Resource Identification Initiative To cite this cell line use: FRDA281 (RRID:CVCL_ZB93)
Comments Part of: Friedreich's ataxia primary fibroblast repository.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
Disease Friedreich ataxia (NCIt: C84718)
Friedreich ataxia (ORDO: Orphanet_95)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 19Y
Category Finite cell line
Publications

PubMed=27002638; DOI=10.1089/bio.2015.0117; PMCID=PMC4991587
Li Y.-J., Polak U., Clark A.D., Bhalla A.D., Chen Y.-Y., Li J.-X., Farmer J., Seyer L., Lynch D.R., Butler J.S., Napierala M.
Establishment and maintenance of primary fibroblast repositories for rare diseases -- Friedreich's ataxia example.
Biopreserv. Biobank. 14:324-329(2016)

PubMed=29125828; DOI=10.1242/dmm.030536; PMCID=PMC5719256
Napierala J.S., Li Y.-J., Lu Y., Lin K., Hauser L.A., Lynch D.R., Napierala M.
Comprehensive analysis of gene expression patterns in Friedreich's ataxia fibroblasts by RNA sequencing reveals altered levels of protein synthesis factors and solute carriers.
Dis. Model. Mech. 10:1353-1369(2017)

PubMed=32291635; DOI=10.1007/s12035-020-01899-1; PMCID=PMC7253519
Misiorek J.O., Schreiber A.M., Urbanek-Trzeciak M.O., Hauser L.A., Lynch D.R., Napierala J.S., Napierala M.
A comprehensive transcriptome analysis identifies FXN and BDNF as novel targets of miRNAs in Friedreich's ataxia patients.
Mol. Neurobiol. 57:2639-2653(2020)

Cross-references
Cell line collections (Providers) ABM; T5446
Encyclopedic resources Wikidata; Q98126248
Gene expression databases GEO; GSM2794422
Entry history
Entry creation02-Jul-2020
Last entry update10-Apr-2025
Version number9