Cellosaurus logo
expasy logo

Cellosaurus MDCC-UA23 (CVCL_ZB70)

[Text version]
Cell line name MDCC-UA23
Synonyms UA23
Accession CVCL_ZB70
Resource Identification Initiative To cite this cell line use: MDCC-UA23 (RRID:CVCL_ZB70)
Comments Group: Bird cell line.
Characteristics: The MDV RB-1b virus has been modified by insertion of a soluble modified derivative of GFP (smGFP) downstream of the pp38 protein of MDV. Thus the expression of GFP is induced during reactivation of the MDV from latency, therefore these cells are ideal for studying the early events of reactivation.
Genetic integration: Method=Transduction; Gene=FPbase; 1XF1B; GFP (Note=avGFP; original A.victoria green fluorescent protein).
Transformant: NCBI_TaxID; 33707; Gallid herpesvirus 2 (Marek's disease virus) (strain RB-1b) (Note=RB-1B-pp38smGFP).
Derived from site: In situ; Testis; UBERON=UBERON_0000473.
Disease Marek disease (NCIt: C84884)
Species of origin Gallus gallus (Chicken) (NCBI Taxonomy: 9031)
Breed/subspecies: White Leghorn; VBO=VBO_0000646.
Sex of cell Male
Category Cancer cell line
Publications

PubMed=15529969; DOI=10.1637/7110
Prigge J.T., Majerciak V., Hunt H.D., Dienglewicz R.L., Parcells M.S.
Construction and characterization of Marek's disease viruses having green fluorescent protein expression tied directly or indirectly to phosphoprotein 38 expression.
Avian Dis. 48:471-487(2004)

Cross-references
Encyclopedic resources Wikidata; Q98127140
Entry history
Entry creation02-Jul-2020
Last entry update19-Dec-2024
Version number7