Cellosaurus logo
expasy logo

Cellosaurus C6 rho-0#14 (CVCL_ZB60)

[Text version]
Cell line name C6 rho-0#14
Accession CVCL_ZB60
Resource Identification Initiative To cite this cell line use: C6 rho-0#14 (RRID:CVCL_ZB60)
Comments Characteristics: Cell line devoid of mitochondrial DNA (rho0). Produced by transient transfection with plasmid pMA4008 encoding HSV-1 UL12.5M185 protein, which damages mtDNA by an unknown mechanism.
Transformant: ChEBI; CHEBI:50102; N-methyl-N-nitrosourea (NMU).
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Disease Rat malignant glioma (NCIt: C64069)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Wistar Furth; RS=RS:0000982.
Hierarchy Parent: CVCL_0194 (C6)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=27136098; DOI=10.1371/journal.pone.0154684; PMCID=PMC4852919
Spadafora D., Kozhukhar N., Chouljenko V.N., Kousoulas K.G., Alexeyev M.F.
Methods for efficient elimination of mitochondrial DNA from cultured cells.
PLoS ONE 11:E0154684-E0154684(2016)

Cross-references
Cell line collections (Providers) Kerafast; ESA107
Encyclopedic resources Wikidata; Q98125601
Entry history
Entry creation02-Jul-2020
Last entry update10-Sep-2024
Version number5