Cellosaurus NFkappaB-TIME (CVCL_Z064)
| Cell line name | NFkappaB-TIME | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Accession | CVCL_Z064 | ||||||||||||||||||
| Resource Identification Initiative | To cite this cell line use: NFkappaB-TIME (RRID:CVCL_Z064) | ||||||||||||||||||
| Comments | Characteristics: The NanoLuc reporter gene is under the control of multiple copies of the NF-kappaB response element (ATCC=CRL-4049). Characteristics: When cells are exposed to inflammatory cytokines such as TNFalpha, activation of the NF-kappaB signaling pathway occurs resulting in increased luciferase activity (ATCC=CRL-4049). Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT. Genetic integration: Method=Transduction; Gene=UniProtKB; P33967; B.cereus Bsr. Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Genetic integration: Method=Transfection; Gene=NanoLuc (Note=19 kDa ATP-independent bright luminescent protein derived from O.gracilirostris). Derived from site: In situ; Foreskin, skin, dermis, microvascular endothelium; UBERON=UBERON_0001471+UBERON_0008339. | ||||||||||||||||||
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||
| Hierarchy | Parent: CVCL_0047 (TIME) | ||||||||||||||||||
| Sex of cell | Male | ||||||||||||||||||
| Age at sampling | <1M | ||||||||||||||||||
| Category | Telomerase immortalized cell line | ||||||||||||||||||
| STR profile | Source(s): ATCC=CRL-4049 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
| Cross-references | |||||||||||||||||||
| Cell line collections (Providers) | ATCC; CRL-4049 | ||||||||||||||||||
| Encyclopedic resources | Wikidata; Q54930430 | ||||||||||||||||||
| Entry history | |||||||||||||||||||
| Entry creation | 10-Apr-2015 | ||||||||||||||||||
| Last entry update | 10-Apr-2025 | ||||||||||||||||||
| Version number | 16 | ||||||||||||||||||