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Cellosaurus 293T/ACE2 [USA 2003] (CVCL_YZ65)

[Text version]
Cell line name 293T/ACE2 [USA 2003]
Accession CVCL_YZ65
Resource Identification Initiative To cite this cell line use: 293T/ACE2 [USA 2003] (RRID:CVCL_YZ65)
Comments Group: SARS-CoV-2 research cell line.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:13557; ACE2.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA).
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0063 (HEK293T)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=14647384; DOI=10.1038/nature02145; PMCID=PMC7095016
Li W.-H., Moore M.J., Vasilieva N., Sui J.-H., Wong S.K., Berne M.A., Somasundaran M., Sullivan J.L., Luzuriaga K., Greenough T.C., Choe H., Farzan M.R.
Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus.
Nature 426:450-454(2003)

Cross-references
Encyclopedic resources Wikidata; Q98125378
Entry history
Entry creation02-Jul-2020
Last entry update19-Dec-2024
Version number9