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Cellosaurus FHS062i-sh521E (CVCL_YY93)

[Text version]
Cell line name FHS062i-sh521E
Synonyms iPSC - 521E
Accession CVCL_YY93
Resource Identification Initiative To cite this cell line use: FHS062i-sh521E (RRID:CVCL_YY93)
Comments Part of: Framingham Heart Study (FHS) collection.
Part of: Next Generation Genetic Association studies (Next Gen) program cell lines.
Population: Caucasian.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; 3231; CELSR2; Simple; c.*919G; dbSNP=rs12740374; Zygosity=Homozygous; Note=Major haplotype (PubMed=28388431).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_YY92 ! FHS061i-sh521C
Sex of cell Male
Age at sampling 61-70Y
Category Induced pluripotent stem cell
Publications

PubMed=28388431; DOI=10.1016/j.stem.2017.01.010
Warren C.R., O'Sullivan J.F., Friesen M., Becker C.E., Zhang X.-L., Liu P.-C., Wakabayashi Y., Morningstar J.E., Shi X., Choi J., Xia F., Peters D.T., Florido M.H.C., Tsankov A.M., Duberow E.A., Comisar L., Shay J., Jiang X., Meissner A., Musunuru K., Kathiresan S., Daheron L., Zhu J., Gerszten R.E., Deo R.C., Vasan R.S., O'Donnell C.J., Cowan C.A.
Induced pluripotent stem cell differentiation enables functional validation of GWAS variants in metabolic disease.
Cell Stem Cell 20:547-557.e7(2017)

Cross-references
Cell line collections (Providers) WiCell; fhs062i-sh521e
Biological sample resources BioSample; SAMN06093653
Encyclopedic resources Wikidata; Q98126228
Gene expression databases GEO; GSM2411790
Entry history
Entry creation02-Jul-2020
Last entry update29-Jun-2023
Version number7