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Cellosaurus HPDE-iKRASwt (CVCL_YY29)

[Text version]
Cell line name HPDE-iKRASwt
Accession CVCL_YY29
Resource Identification Initiative To cite this cell line use: HPDE-iKRASwt (RRID:CVCL_YY29)
Comments Characteristics: Expression the KRAS gene is under the control of doxycycline.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:6407; KRAS.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Donor information: Established from a patient suffering from a cystadenocarcinoma in the tail of her pancreas.
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Cell type: Pancreatic ductal cell; CL=CL_0002079.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0P37 (HPDE6c11)
Sex of cell Female
Age at sampling 63Y
Category Transformed cell line
Publications

PubMed=26806015; DOI=10.1038/ncomms10500; PMCID=PMC4737758
Tsang Y.H., Dogruluk T., Tedeschi P.M., Wardwell-Ozgo J., Lu H.-Y., Espitia M., Nair N., Minelli R., Chong Z.-C., Chen F.-J., Chang Q.E., Dennison J.B., Dogruluk A., Li M., Ying H.-Q., Bertino J.R., Gingras M.-C., Ittmann M., Kerrigan J., Chen K., Creighton C.J., Eterovic A.K., Mills G.B., Scott K.L.
Functional annotation of rare gene aberration drivers of pancreatic cancer.
Nat. Commun. 7:10500.1-10500.11(2016)

Cross-references
Encyclopedic resources Wikidata; Q98126698
Entry history
Entry creation02-Jul-2020
Last entry update19-Dec-2024
Version number11