ID   B2M-/Etrimer Elf1
AC   CVCL_YY10
DR   WiCell; b2m-etrimer-elf1
DR   Wikidata; Q98125536
RX   PubMed=28504668;
CC   Characteristics: Using a rAAV, the second B2M allele has been edited to express the signal sequence of HLA-G followed by a flexible (G4S)3 linker followed by B2M covalently linked at the C-terminus to a flexible (G4S)4 linker followed by HLA-E.
CC   Knockout cell: Method=Recombinant Adeno-Associated Virus; HGNC; 914; B2M (Note=1 of 2 alleles).
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_C115 ! Elf1
SX   Female
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 02-07-20; Last updated: 30-01-24; Version: 5
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RX   PubMed=28504668; DOI=10.1038/nbt.3860; PMCID=PMC5548598;
RA   Gornalusse G.G., Hirata R.K., Funk S.E., Riolobos L., Lopes V.S.,
RA   Manske G., Prunkard D., Colunga A.G., Hanafi L.-A., Clegg D.O.,
RA   Turtle C., Russell D.W.;
RT   "HLA-E-expressing pluripotent stem cells escape allogeneic responses
RT   and lysis by NK cells.";
RL   Nat. Biotechnol. 35:765-772(2017).
//