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Cellosaurus HCC1428-LTED (CVCL_YX83)

[Text version]
Cell line name HCC1428-LTED
Synonyms HCC1428 LTED; HCC1428-Long Term Estrogen-Deprived
Accession CVCL_YX83
Resource Identification Initiative To cite this cell line use: HCC1428-LTED (RRID:CVCL_YX83)
Comments Population: Caucasian.
Characteristics: Derived from parent cell line by long-term culture in the presence of RPMI-1640 medium containing 10% dextran charcoal stripped serum (DCC) (PubMed=26116361).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; 73; ABCG1 + HGNC; 11024; SLC37A1; Name(s)=SLC37A1-ABCG1 (from parent cell line).
  • Mutation; HGNC; 3701; FHIT; Unexplicit; Ex4del; Zygosity=Homozygous (from parent cell line).
Disease Breast adenocarcinoma (NCIt: C5214)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1252 (HCC1428)
Sex of cell Female
Age at sampling 49Y
Category Cancer cell line

PubMed=26116361; DOI=10.1158/1535-7163.MCT-15-0143
Ribas R., Pancholi S., Guest S.K., Marangoni E., Gao Q., Thuleau A., Simigdala N., Polanska U.M., Campbell H., Rani A., Liccardi G., Johnston S.R.D., Davies B.R., Dowsett M., Martin L.-A.
AKT antagonist AZD5363 influences estrogen receptor function in endocrine-resistant breast cancer and synergizes with fulvestrant (ICI182780) in vivo.
Mol. Cancer Ther. 14:2035-2048(2015)

Encyclopedic resources Wikidata; Q93982296
Entry history
Entry creation12-Mar-2020
Last entry update29-Jun-2023
Version number10