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Cellosaurus A20 NF-kappaB (CVCL_YU22)

[Text version]
Cell line name A20 NF-kappaB
Synonyms A20_NF-kappaB
Accession CVCL_YU22
Resource Identification Initiative To cite this cell line use: A20 NF-kappaB (RRID:CVCL_YU22)
Comments Characteristics: Reporter cell line for the measurement of the biological activity of a wide variety of cytokines.
Characteristics: Activated by NF-kappaB through a NF-kappaB response element fused to a secNanoLuc-T2A-mCherry construct.
Transfected with: NanoLuc, a 19 kDa ATP-independent bright luminescent protein derived from Oplophorus gracilirostris.
Transfected with: UniProtKB; X5DSL3; Anaplasma marginale mCherry fluorescent protein.
Cell type: B-cell; CL=CL_0000236.
Disease Mouse reticulum cell sarcoma (NCIt: C134780)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/cAnN.
Hierarchy Parent: CVCL_1940 (A20)
Sex of cell Sex unspecified
Age at sampling >15M
Category Cancer cell line

PubMed=32094407; DOI=10.1038/s41598-020-60182-4
Mock J., Pellegrino C., Neri D.
A universal reporter cell line for bioactivity evaluation of engineered cytokine products.
Sci. Rep. 10:3234-3234(2020)

Encyclopedic resources Wikidata; Q93311424
Entry history
Entry creation12-Mar-2020
Last entry update05-Oct-2023
Version number7