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Cellosaurus SK-OV-3-hCD271 (CVCL_YU10)

[Text version]
Cell line name SK-OV-3-hCD271
Synonyms SK-OV-3-CD271
Accession CVCL_YU10
Resource Identification Initiative To cite this cell line use: SK-OV-3-hCD271 (RRID:CVCL_YU10)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:7809; NGFR.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Leufs*9 (c.4666delA); ClinVar=VCV000156477; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.Arg505Leu (c.1514G>T); ClinVar=VCV000376424; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser90Profs*33 (c.267delC); ClinVar=VCV000156515; Zygosity=Homozygous (from parent cell line).
Disease Ovarian serous cystadenocarcinoma (NCIt: C7978)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0532 (SK-OV-3)
Sex of cell Female
Age at sampling 64Y
Category Cancer cell line
Publications

PubMed=32069133; DOI=10.1089/mab.2019.0040
Morita S., Mochizuki M., Shibuya-Takahashi R., Nakamura-Shima M., Yamazaki T., Imai T., Asada Y., Matsuura K., Kawamura S., Yamaguchi K., Yasuda J., Sugamura K., Katori Y., Satoh K., Tamai K.
Establishment of a monoclonal antibody that recognizes cysteine-rich domain 1 of human CD271.
Monoclon. Antib. Immunodiagn. Immunother. 39:6-11(2020)

Cross-references
Cell line databases/resources cancercelllines; CVCL_YU10
Encyclopedic resources Wikidata; Q98132669
Entry history
Entry creation12-Mar-2020
Last entry update19-Dec-2024
Version number10