Cellosaurus cell line H58 (CVCL

Cellosaurus H58 (CVCL_YP34)

[Text version]

Cell line name

H58

Accession

CVCL_YP34

Resource Identification Initiative

To cite this cell line use: H58 (RRID:CVCL_YP34)

Comments

Doubling time: 36 hours (PubMed=32005909).
Omics: Deep exome analysis.
Omics: Genome sequenced.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.

Sequence variations

Gene fusion; HGNC; HGNC:22170; BCAR4 + HGNC; HGNC:30959; ZC3H7A; Name(s)=ZC3H7A-BCAR4 (PubMed=32005909).
Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1175Ter (c.3523C>T); ClinVar=VCV000537459; Zygosity=Unspecified (PubMed=32005909).
Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Ser45Phe (c.134C>T); ClinVar=VCV000017588; Zygosity=Unspecified (PubMed=32005909).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Unspecified (PubMed=32005909).

Disease

Pancreatic intraductal tubulopapillary neoplasm (NCIt: C95506)
Intraductal tubulopapillary neoplasm of pancreas (ORDO: Orphanet_580572)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

60-69Y

Category

Cancer cell line

STR profile

Source(s): PubMed=32005909

Markers:

Amelogenin	X,Y
CSF1PO	12
D5S818	12
D7S820	11,12
D13S317	9,11
D16S539	11,13
D21S11	28,30
TH01	6,9.3
TPOX	8,11
vWA	16,17

Publications

PubMed=32005909; DOI=10.1038/s41374-020-0372-0; PMCID=PMC7316603
Felsenstein M., Trujillo M.A., Huang B., Nanda N., Jiang Z.-D., Jeong Y.J., Pfluger M., Goggins M.G., Hruban R.H., Thompson E.D., Heaphy C.M., Roberts N.J., Wood L.D.
Generation and characterization of a cell line from an intraductal tubulopapillary neoplasm of the pancreas.
Lab. Invest. 100:1003-1013(2020)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_YP34

Encyclopedic resources

Wikidata; Q93937071

Entry history

Entry creation

12-Mar-2020

Last entry update

19-Dec-2024

Version number