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Cellosaurus SPC-A-1BM (CVCL_YP05)

[Text version]
Cell line name SPC-A-1BM
Accession CVCL_YP05
Resource Identification Initiative To cite this cell line use: SPC-A-1BM (RRID:CVCL_YP05)
Comments Problematic cell line: Contaminated. Parent cell line (SPC-A1) has been shown to be a HeLa derivative.
Population: African American.
Characteristics: Bone metastatic phenotype. Obtained after 8 serial passages of the parent cell line by injection into the left cardiac ventricle of NIH-Beige-Nude-XID immunodeficient mice and retrieval of the bone metastatic lesions.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6955 (SPC-A1)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line

PubMed=19324277; DOI=10.1016/j.nucmedbio.2008.12.007
Yang S.-F., Dong Q.-G., Yao M., Shi M.-P., Ye J.-D., Zhao L.-X., Su J.-Z., Gu W.-Y., Xie W.-H., Wang K.-K., Du Y.-Z., Li Y., Huang Y.
Establishment of an experimental human lung adenocarcinoma cell line SPC-A-1BM with high bone metastases potency by (99m)Tc-MDP bone scintigraphy.
Nucl. Med. Biol. 36:313-321(2009)

Encyclopedic resources Wikidata; Q98132810
Entry history
Entry creation12-Mar-2020
Last entry update05-Oct-2023
Version number5