ID   UWG02CTC
AC   CVCL_YN87
SY   University of Wollongong Gastric cancer 02 Circulating Tumor Cells
DR   cancercelllines; CVCL_YN87
DR   Wikidata; Q98134460
RX   PubMed=31953491;
CC   Doubling time: 18 hours (Direct_author_submission).
CC   Sequence variation: Mutation; HGNC; HGNC:2348; CREBBP; Simple; p.Arg1446Cys (c.4336C>T); ClinVar=VCV000095047; Zygosity=Heterozygous (PubMed=31953491).
CC   Sequence variation: Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Ser33Phe (c.98C>T); ClinVar=VCV000017583; Zygosity=Heterozygous (PubMed=31953491).
CC   Sequence variation: Mutation; HGNC; HGNC:4392; GNAS; Simple; p.Arg201His (c.602G>A); ClinVar=VCV000015934; Zygosity=Heterozygous (PubMed=31953491).
CC   Sequence variation: Mutation; HGNC; HGNC:7029; MET; Simple; p.Thr992Ile (c.2975C>T) (p.Thr1010Ile, c.3029C>T); ClinVar=VCV000041624; Zygosity=Heterozygous (PubMed=31953491).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu418Lys (c.1252G>A); ClinVar=VCV000045464; Zygosity=Heterozygous (PubMed=31953491).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu542Gln (c.1624G>C); ClinVar=VCV000376244; Zygosity=Heterozygous (PubMed=31953491).
CC   Sequence variation: Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Asp537His (c.1609G>C); Zygosity=Homozygous (PubMed=31953491).
CC   Miscellaneous: Age of donor, doubling time and zygosity of sequence variations from personal communication of Brungs, Daniel.
CC   Derived from site: Metastatic; Peripheral blood; UBERON=UBERON_0000178.
ST   Source(s): PubMed=31953491
ST   Amelogenin: X,Y
ST   CSF1PO: 10,12
ST   D13S317: 12
ST   D16S539: 11
ST   D18S51: 14
ST   D19S433: 13,15
ST   D21S11: 30,31
ST   D2S1338: 19
ST   D3S1358: 15,16
ST   D5S818: 12
ST   D7S820: 11,12
ST   D8S1179: 11,13
ST   FGA: 22,23
ST   Penta D: 9,14
ST   Penta E: 7
ST   TH01: 6,7
ST   TPOX: 8
ST   vWA: 16
DI   NCIt; C4004; Gastric adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_YN86 ! UWG02ASC
SX   Male
AG   61Y
CA   Cancer cell line
DT   Created: 12-03-20; Last updated: 19-12-24; Version: 10
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RX   PubMed=31953491; DOI=10.1038/s41598-019-57164-6; PMCID=PMC6968999;
RA   Brungs D., Minaei E., Piper A.-K., Perry J.R., Splitt A., Carolan M.G.,
RA   Ryan S., Wu X.J., Corde S., Tehei M., Aghmesheh M., Vine K.L.,
RA   Becker T.M., Ranson M.;
RT   "Establishment of novel long-term cultures from EpCAM positive and
RT   negative circulating tumour cells from patients with metastatic
RT   gastroesophageal cancer.";
RL   Sci. Rep. 10:539-539(2020).
//