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Cellosaurus AG27607 (CVCL_YN67)

[Text version]
Cell line name AG27607
Synonyms AG27607*C
Accession CVCL_YN67
Resource Identification Initiative To cite this cell line use: AG27607 (RRID:CVCL_YN67)
Comments Population: Caucasian.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; HGNC:613; APOE; Simple; p.Arg176Cys (c.526C>T); ClinVar=VCV000017848; Zygosity=Heterozygous; Note=ApoE2 allele (Coriell=AG27607).
Disease Alzheimer's disease (NCIt: C2866)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2Y81 (AG21158)
Sex of cell Female
Age at sampling 69Y
Category Induced pluripotent stem cell
Publications

PubMed=30699343; DOI=10.1016/j.celrep.2019.01.023; PMCID=PMC6386196
Meyer K., Feldman H.M., Lu T., Drake D., Lim E.T., Ling K.-H., Bishop N.A., Pan Y., Seo J., Lin Y.-T., Su S.C., Church G.M., Tsai L.-H., Yankner B.A.
REST and neural gene network dysregulation in iPSC models of Alzheimer's disease.
Cell Rep. 26:1112-1127.e9(2019)

Cross-references
Cell line collections (Providers) Coriell; AG27607
Encyclopedic resources Wikidata; Q93323511
Entry history
Entry creation12-Mar-2020
Last entry update19-Dec-2024
Version number10