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Cellosaurus 6499c4 (CVCL_YM26)

[Text version]
Cell line name 6499c4
Accession CVCL_YM26
Resource Identification Initiative To cite this cell line use: 6499c4 (RRID:CVCL_YM26)
Comments Genetic integration: Method=Transgenic mouse; Gene=FPbase; 8DNLG; YFP (Note=EYFP, yellow fluorescent protein derived from GFP).
Genetic integration: Method=Transgenic mouse; Gene=MGI; MGI:96680; Kras (Note=With p.Gly12Asp).
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Breed/subspecies: KrasLSL-G12D/+;Trp53LSL-R172H/+;Pdx1-Cre;Rosa26YFP/YFP (KPCY).
Disease Mouse pancreatic neoplasm (NCIt: C34035)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Originate from same individual CVCL_YM25 ! 6499c3
Category Cancer cell line
Publications

PubMed=29958801; DOI=10.1016/j.immuni.2018.06.006; PMCID=PMC6707727
Li J.-Y., Byrne K.T., Yan F.-X., Yamazoe T., Chen Z.-Y., Baslan T., Richman L.P., Lin J.H., Sun Y.H., Rech A.J., Balli D., Hay C.A., Sela Y., Merrell A.J., Liudahl S.M., Gordon N., Norgard R.J., Yuan S., Yu S.-X., Chao T., Ye S., Eisinger-Mathason T.S.K., Faryabi R.B., Tobias J.W., Lowe S.W., Coussens L.M., Wherry E.J. 3rd, Vonderheide R.H., Stanger B.Z.
Tumor cell-intrinsic factors underlie heterogeneity of immune cell infiltration and response to immunotherapy.
Immunity 49:178-193.e7(2018)

Cross-references
Cell line collections (Providers) Kerafast; EUP015-FP
Encyclopedic resources Wikidata; Q93308900
Gene expression databases GEO; GSM2974127
GEO; GSM2974128
GEO; GSM2974213
GEO; GSM2974922
GEO; GSM2974923
Entry history
Entry creation12-Mar-2020
Last entry update10-Apr-2025
Version number6