Cellosaurus cell line 6419c5 (CVCL

Cellosaurus 6419c5 (CVCL_YM21)

Cross-references
Cell line name	6419c5
Accession	CVCL_YM21
Resource Identification Initiative	To cite this cell line use: 6419c5 (RRID:CVCL_YM21)
Comments	Genetic integration: Method=Transgenic mouse; Gene=FPbase; 8DNLG; YFP (Note=EYFP, yellow fluorescent protein derived from GFP). Genetic integration: Method=Transgenic mouse; Gene=MGI; MGI:96680; Kras (Note=With p.Gly12Asp). Omics: Transcriptomics; RNAseq. Derived from site: In situ; Pancreas; UBERON=UBERON_0001264. Breed/subspecies: KrasLSL-G12D/+;Trp53LSL-R172H/+;Pdx1-Cre;Rosa26YFP/YFP (KPCY).
Disease	Mouse pancreatic neoplasm (NCIt: C34035)
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Originate from same individual	CVCL_YM20 ! 6419c1
Category	Cancer cell line
Publications	PubMed=29958801; DOI=10.1016/j.immuni.2018.06.006; PMCID=PMC6707727 Li J.-Y., Byrne K.T., Yan F.-X., Yamazoe T., Chen Z.-Y., Baslan T., Richman L.P., Lin J.H., Sun Y.H., Rech A.J., Balli D., Hay C.A., Sela Y., Merrell A.J., Liudahl S.M., Gordon N., Norgard R.J., Yuan S., Yu S.-X., Chao T., Ye S., Eisinger-Mathason T.S.K., Faryabi R.B., Tobias J.W., Lowe S.W., Coussens L.M., Wherry E.J. 3rd, Vonderheide R.H., Stanger B.Z. Tumor cell-intrinsic factors underlie heterogeneity of immune cell infiltration and response to immunotherapy. Immunity 49:178-193.e7(2018)
Cell line collections (Providers)	Kerafast; EUP005-FP
Encyclopedic resources	Wikidata; Q93308853
Gene expression databases	GEO; GSM2974157 GEO; GSM2974158 GEO; GSM2974208 GEO; GSM2974913 GEO; GSM2974914
Entry history
Entry creation	12-Mar-2020
Last entry update	10-Apr-2025
Version number	6