Cellosaurus HEK293 CCKBR arrestin-Nomad (CVCL_YK05)
| Cell line name | HEK293 CCKBR arrestin-Nomad |
|---|---|
| Synonyms | CCK2 Arrestin-Nomad; ArrestNomad-CCKBR |
| Accession | CVCL_YK05 |
| Resource Identification Initiative | To cite this cell line use: HEK293 CCKBR arrestin-Nomad (RRID:CVCL_YK05) |
| Comments | Characteristics: In basal conditions, the arrestin Biosensor shows a very low fluorescence intensity. When an agonist binds to CCKBR, it is phosphorylated, promoting the recruitment of the arrestin-Nomad Biosensor and leading to a change in its structural folding and promoting an increase in fluorescence intensity. Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:1571; CCKBR. Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:712; ARRB2. Genetic integration: Method=Transfection/transduction; Gene=FPbase; A315M; TurboGFP (Note=Green fluorescent protein from P.plumata). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR). Transformant: NCBI_TaxID; 28285; Adenovirus 5. Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_0045 (HEK293) |
| Sex of cell | Female |
| Age at sampling | Fetus |
| Category | Transformed cell line |
| Cross-references | |
| Cell line collections (Providers) | Innoprot; P70808 |
| Encyclopedic resources | Wikidata; Q94092845 |
| Entry history | |
| Entry creation | 19-Dec-2019 |
| Last entry update | 19-Dec-2024 |
| Version number | 11 |