ID   PGA-1
AC   CVCL_Y545
SY   PGA1; PG A1; CLL-PGA
DR   ArrayExpress; E-MTAB-7721
DR   ArrayExpress; E-MTAB-7722
DR   cancercelllines; CVCL_Y545
DR   Cell_Model_Passport; SIDM01855
DR   DepMap; ACH-001634
DR   DSMZ; ACC-766
DR   DSMZCellDive; ACC-766
DR   NCBI_Iran; C583
DR   Wikidata; Q54947324
RX   PubMed=2836321;
RX   PubMed=23297799;
RX   PubMed=31160637;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: LL-100 blood cancer cell line panel.
CC   Population: Caucasian.
CC   Doubling time: ~50 hours (DSMZ=ACC-766).
CC   HLA typing: A*02:01:01,03:01:01; B*35:03:01,39:01:01; C*07:02:01,12:03:01; DPA1*01:03:01,01:03:01; DPB1*04:02:01,02:01:02; DQA1*01:02:01,05:05:01; DQB1*03:01:01,06:09:01; DRA*01:02:02,01:02:02; DRB1*12:01:01,13:02:01 (DSMZCellDive=ACC-766).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Omics: Deep exome analysis.
CC   Omics: Transcriptome analysis by RNAseq.
ST   Source(s): DepMap=ACH-001634; DSMZ=ACC-766
ST   Amelogenin: X,Y
ST   CSF1PO: 13
ST   D13S317: 8,12
ST   D16S539: 12
ST   D18S51: 15
ST   D19S433: 14,15
ST   D21S11: 28,30
ST   D2S1338: 17,18
ST   D3S1358: 15,16
ST   D5S818: 11,12
ST   D7S820: 10,11
ST   D8S1179: 13
ST   FGA: 20,22
ST   Penta D: 9,14
ST   Penta E: 12
ST   TH01: 6,9.3
ST   TPOX: 8,11
ST   vWA: 17
DI   NCIt; C3163; Chronic lymphocytic leukemia
DI   ORDO; Orphanet_67038; B-cell chronic lymphocytic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_Y555 ! PG/B95-8
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 07-11-14; Last updated: 02-05-24; Version: 14
//
RX   PubMed=2836321; DOI=10.1002/ijc.2910410621;
RA   Lewin N., Aman P., Mellstedt H., Zech L., Klein G.;
RT   "Direct outgrowth of in vivo Epstein-Barr virus (EBV)-infected chronic
RT   lymphocytic leukemia (CLL) cells into permanent lines.";
RL   Int. J. Cancer 41:892-895(1988).
//
RX   PubMed=23297799; DOI=10.3109/10428194.2013.764418;
RA   Myhrinder A.L., Hellqvist E., Bergh A.-C., Jansson M.,
RA   Nilsson K., Hultman P., Jonasson J., Buhl A.M., Pedersen L.B.,
RA   Jurlander J., Klein E., Weit N., Herling M., Rosenquist R., Rosen A.;
RT   "Molecular characterization of neoplastic and normal 'sister'
RT   lymphoblastoid B-cell lines from chronic lymphocytic leukemia.";
RL   Leuk. Lymphoma 54:1769-1779(2013).
//
RX   PubMed=31160637; DOI=10.1038/s41598-019-44491-x;
RA   Quentmeier H., Pommerenke C., Dirks W.G., Eberth S., Koeppel M.,
RA   MacLeod R.A.F., Nagel S., Steube K., Uphoff C.C., Drexler H.G.;
RT   "The LL-100 panel: 100 cell lines for blood cancer studies.";
RL   Sci. Rep. 9:8218-8218(2019).
//