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Cellosaurus DF15R (CVCL_Y430)

[Text version]
Cell line name DF15R
Accession CVCL_Y430
Resource Identification Initiative To cite this cell line use: DF15R (RRID:CVCL_Y430)
Comments Selected for resistance to: ChEBI; CHEBI_72690; Pomalidomide (3-amino-thalidomide; CC-4047).
Cell type: B-cell; CL=CL_0000236.
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_Y429 (DF15)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=22552008; DOI=10.1038/leu.2012.119; PMCID=PMC3496085
Lopez-Girona A., Mendy D., Ito T., Miller K., Gandhi A.K., Kang J., Karasawa S., Carmel G., Jackson P., Abbasian M., Mahmoudi A., Cathers B., Rychak E., Gaidarova S., Chen R., Schafer P.H., Handa H., Daniel T.O., Evans J.F., Chopra R.
Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide.
Leukemia 26:2326-2335(2012)

Cross-references
Encyclopedic resources Wikidata; Q54831024
Entry history
Entry creation07-Nov-2014
Last entry update19-Dec-2024
Version number7