Cellosaurus cell line SZ-FX6 (CVCL

Cellosaurus SZ-FX6 (CVCL_Y335)

Cross-references
Cell line name	SZ-FX6
Synonyms	SZ-FX6 PGD; FX#6
Accession	CVCL_Y335
Resource Identification Initiative	To cite this cell line use: SZ-FX6 (RRID:CVCL_Y335)
Comments	From: Shaare Zedek Medical Center, The Hebrew University; Jerusalem; Israel. Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-20-0443. Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358. Cell type: Embryonic stem cell; CL=CL_0002322.
Sequence variations	Mutation; HGNC; HGNC:3775; FMR1; Repeat_expansion; CGG[170]; ClinVar=VCV000009972; Zygosity=Hemizygous (PubMed=21585244).
Disease	Fragile X syndrome (NCIt: C84717) Fragile X syndrome (ORDO: Orphanet_908)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	Blastocyst stage
Category	Embryonic stem cell
Web pages	https://www.szmc.org.il/UploadFiles/12_2016/HESC.pdf
Publications	PubMed=21585244; DOI=10.1089/scd.2011.0102; PMCID=PMC3272241 Ben-Yosef D., Amit A., Malcov M., Frumkin T., Ben-Yehudah A., Eldar I., Mey-Raz N., Azem F., Altarescu G., Renbaum P., Beeri R., Varshaver I., Eldar-Geva T., Epsztejn-Litman S., Levy-Lahad E., Eiges R. Female sex bias in human embryonic stem cell lines. Stem Cells Dev. 21:363-372(2012) PubMed=27690107; DOI=10.3390/genes7100077; PMCID=PMC5083916 Mor-Shaked H., Eiges R. Modeling fragile X syndrome using human pluripotent stem cells. Genes (Basel) 7:77.1-77.19(2016)
Cell line databases/resources	NIHhESC; NIHhESC-20-0443
Encyclopedic resources	Wikidata; Q54971311
Entry history
Entry creation	07-Nov-2014
Last entry update	19-Dec-2024
Version number	12