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Cellosaurus BXD-1425EPN (CVCL_Y105)

[Text version]
Cell line name BXD-1425EPN
Synonyms BXD1425EPN; Baylor Xenograft Derived-1425EPN
Accession CVCL_Y105
Resource Identification Initiative To cite this cell line use: BXD-1425EPN (RRID:CVCL_Y105)
Comments Characteristics: Established from a second generation patient-derived xenograft established in the brain of RAG2/SCID mice.
Disease Ependymoma (NCIt: C3017)
Ependymoma (ORDO: Orphanet_251636)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 9Y
Category Cancer cell line
Publications

PubMed=20511191; DOI=10.1093/neuonc/nop056; PMCID=PMC2940646
Yu L.-T., Baxter P.A., Voicu H., Gurusiddappa S., Zhao Y.-J., Adesina A., Man T.-K., Shu Q., Zhang Y.-J., Zhao X.-M., Su J.M., Perlaky L., Dauser R., Chintagumpala M., Lau C.C., Blaney S.M., Rao P.H., Leung H.-C.E., Li X.-N.
A clinically relevant orthotopic xenograft model of ependymoma that maintains the genomic signature of the primary tumor and preserves cancer stem cells in vivo.
Neuro-oncol. 12:580-594(2010)

Cross-references
Encyclopedic resources Wikidata; Q54798747
Entry history
Entry creation07-Nov-2014
Last entry update21-Mar-2023
Version number8