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Cellosaurus OV(hyg)CAR3 (CVCL_Y033)

[Text version]
Cell line name OV(hyg)CAR3
Synonyms Ov(hyg)CAR3
Accession CVCL_Y033
Resource Identification Initiative To cite this cell line use: OV(hyg)CAR3 (RRID:CVCL_Y033)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_16976; Hygromycin B.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; HGNC:8979; PIK3R1; Simple; c.1746-2A>T; Zygosity=Heterozygous; Note=Splice acceptor mutation (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
Disease High grade ovarian serous adenocarcinoma (NCIt: C105555)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0465 (OVCAR-3)
Sex of cell Female
Age at sampling 60Y
Category Cancer cell line
Publications

PubMed=8824553; DOI=10.1002/(SICI)1097-0215(19960917)67:6<816::AID-IJC10>3.0.CO;2-#
Mullen P., Ritchie A., Langdon S.P., Miller W.R.
Effect of Matrigel on the tumorigenicity of human breast and ovarian carcinoma cell lines.
Int. J. Cancer 67:816-820(1996)

Cross-references
Cell line databases/resources cancercelllines; CVCL_Y033
Encyclopedic resources Wikidata; Q54936876
Entry history
Entry creation07-Nov-2014
Last entry update19-Dec-2024
Version number14