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Cellosaurus ABC-1#IL-6 (CVCL_Y023)

[Text version]
Cell line name ABC-1#IL-6
Accession CVCL_Y023
Resource Identification Initiative To cite this cell line use: ABC-1#IL-6 (RRID:CVCL_Y023)
Comments Population: Japanese.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:6018; IL6.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Leu858Arg (c.2573T>G); ClinVar=VCV000016609; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro278Ser (c.832C>T); ClinVar=VCV000376642; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1066 (ABC-1)
Sex of cell Male
Age at sampling 47Y
Category Cancer cell line
Publications

PubMed=15185009; DOI=10.1007/s00262-004-0533-9; PMCID=PMC11034254
Yamaji H., Iizasa T., Koh E., Suzuki M., Otsuji M., Chang H., Motohashi S., Yokoi S., Hiroshima K., Tagawa M., Nakayama T., Fujisawa T.
Correlation between interleukin 6 production and tumor proliferation in non-small cell lung cancer.
Cancer Immunol. Immunother. 53:786-792(2004)

Cross-references
Cell line databases/resources cancercelllines; CVCL_Y023
Encyclopedic resources Wikidata; Q54607715
Entry history
Entry creation07-Nov-2014
Last entry update19-Dec-2024
Version number15