Cellosaurus cell line BxPC-3 human CLDN18.2 (CVCL

Cross-references
Cell line name	BxPC-3 human CLDN18.2
Accession	CVCL_XZ31
Resource Identification Initiative	To cite this cell line use: BxPC-3 human CLDN18.2 (RRID:CVCL_XZ31)
Comments	Population: Caucasian. Doubling time: ~30 hours (KYinno=KC-1272). Genetic integration: Method=Transduction; Gene=HGNC; 2039; CLDN18 (Note=Isoform A2). Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR). Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations	Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line). Gene deletion; HGNC; 6770; SMAD4; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; 1097; BRAF; Simple; p.Val487_Pro492delinsAla (c.1460_1474delGTGTAGGTGCTGTCA); Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; 6407; KRAS; None_reported; -; Zygosity=- (from parent cell line). Mutation; HGNC; 11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Homozygous (from parent cell line).
Disease	Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0186 (BxPC-3)
Sex of cell	Female
Age at sampling	61Y
Category	Cancer cell line
Cell line collections (Providers)	KYinno; KC-1272
Cell line databases/resources	cancercelllines; CVCL_XZ31
Encyclopedic resources	Wikidata; Q93433500
Entry history
Entry creation	19-Dec-2019
Last entry update	10-Sep-2024
Version number	9