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Cellosaurus A549 OS8 (CVCL_XY99)

[Text version]
Cell line name A549 OS8
Accession CVCL_XY99
Resource Identification Initiative To cite this cell line use: A549 OS8 (RRID:CVCL_XY99)
Comments Population: Caucasian.
Characteristics: Transfected with the ScFV sequence of anti-human CD3 mAb OKT3 and a C-terminal domain of mouse CD8a which consists of the transmembrane and cytoplasmic domains.
Genetic integration: Method=Transfection; Gene=MGI; MGI:88346; Cd8a (Note=With p.Met1_Tyr196del).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) KYinno; KC-1047
Cell line databases/resources cancercelllines; CVCL_XY99
Encyclopedic resources Wikidata; Q93311932
Entry history
Entry creation19-Dec-2019
Last entry update19-Dec-2024
Version number11