Cellosaurus cell line C3948 (CVCL

Cellosaurus C3948 (CVCL_XY60)

[Text version]

Cell line name

C3948

Accession

CVCL_XY60

Resource Identification Initiative

To cite this cell line use: C3948 (RRID:CVCL_XY60)

Comments

Doubling time: 30 hours (PubMed=31368081).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Thyroid gland; UBERON=UBERON_0002046.

Sequence variations

Mutation; HGNC; HGNC:28648; DIS3L2; Simple; p.Trp361Leu (c.1082G>T); Zygosity=Unspecified (PubMed=31368081).
Mutation; HGNC; HGNC:11389; STK11; Simple; p.Ser216Phe (c.647C>T); ClinVar=VCV000376708; Zygosity=Unspecified (PubMed=31368081).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu346Ter (c.1036G>T); ClinVar=VCV000634697; Zygosity=Hemizygous (PubMed=31368081).

Disease

Thyroid gland anaplastic carcinoma (NCIt: C3878)
Anaplastic thyroid carcinoma (ORDO: Orphanet_142)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

66Y

Category

Cancer cell line

STR profile

Source(s): PubMed=31368081

Markers:

Amelogenin	X
CSF1PO	11
D3S1358	16
D5S818	10
D7S820	10
D8S1179	15
D13S317	12
D16S539	9
D18S51	12
D21S11	31
FGA	26
Penta D	9
Penta E	13,14
TH01	7
TPOX	8
vWA	16

Publications

PubMed=31368081; DOI=10.1007/s12020-019-02009-5
Pinto A.T., Pojo M., Simoes-Pereira J., Roque R., Saramago A., Roque L., Martins C., Andre S., Cabecadas J., Leite V., Cavaco B.M.
Establishment and characterization of a new patient-derived anaplastic thyroid cancer cell line (C3948), obtained through fine-needle aspiration cytology.
Endocrine 66:288-300(2019)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_XY60

Encyclopedic resources

Wikidata; Q93439974

Entry history

Entry creation

19-Dec-2019

Last entry update

19-Dec-2024

Version number