• Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=31541927).
  
• Mutation; HGNC; HGNC:3584; FANCC; Simple; p.Asp23Ilefs*23 (c.67delG) (322delG); ClinVar=VCV000012049; Zygosity=Unspecified (PubMed=15735012).
  
• Mutation; HGNC; HGNC:8975; PIK3CA; Simple; c.1252-1G>A; Zygosity=Heterozygous; Note=Splice acceptor mutation (PubMed=31541927).
  
• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273Leu (c.818G>T); ClinVar=VCV000376655; Zygosity=Homozygous (PubMed=15735012; PubMed=23613873; PubMed=31541927).
  

PubMed=15735012; DOI=10.1158/0008-5472.CAN-04-3665
van Zeeburg H.J.T., Snijders P.J.F., Pals G., Hermsen M.A.J.A., Rooimans M.A., Bagby G., Soulier J., Gluckman E., Wennerberg J., Leemans C.R., Joenje H., Brakenhoff R.H.
Generation and molecular characterization of head and neck squamous cell lines of Fanconi anemia patients.
Cancer Res. 65:1271-1276(2005)

PubMed=23613873; DOI=10.1371/journal.pone.0061555; PMCID=PMC3629194
Martens-de Kemp S.R., Dalm S.U., Wijnolts F.M.J., Brink A., Honeywell R.J., Peters G.J., Braakhuis B.J.M., Brakenhoff R.H.
DNA-bound platinum is the major determinant of cisplatin sensitivity in head and neck squamous carcinoma cells.
PLoS ONE 8:E61555-E61555(2013)

PubMed=25609062; DOI=10.1158/1078-0432.CCR-14-2616; PMCID=PMC4401632
Lombardi A.J., Hoskins E.E., Foglesong G.D., Wikenheiser-Brokamp K.A., Wiesmuller L., Hanenberg H., Andreassen P.R., Jacobs A.J., Olson S.B., Keeble W.W., Hays L.E., Wells S.I.
Acquisition of relative interstrand crosslinker resistance and PARP inhibitor sensitivity in Fanconi anemia head and neck cancers.
Clin. Cancer Res. 21:1962-1972(2015)

PubMed=26122845; DOI=10.1158/0008-5472.CAN-15-0528
Stoepker C., Ameziane N., van der Lelij P., Kooi I.E., Oostra A.B., Rooimans M.A., van Mil S.E., Brink A., Dietrich R., Balk J.A., Ylstra B., Joenje H., Feller S.M., Brakenhoff R.H.
Defects in the Fanconi anemia pathway and chromatid cohesion in head and neck cancer.
Cancer Res. 75:3543-3553(2015)

PubMed=31541927; DOI=10.1016/j.oraloncology.2019.09.004; PMCID=PMC7372097
van Harten A.M., Poell J.B., Buijze M., Brink A., Wells S.I., Leemans C.R., Wolthuis R.M.F., Brakenhoff R.H.
Characterization of a head and neck cancer-derived cell line panel confirms the distinct TP53-proficient copy number-silent subclass.
Oral Oncol. 98:53-61(2019)

PubMed=36912284; DOI=10.1002/ijc.34506
Nguyen H.T., Tang W.-L., Webster A.L.H., Whiteaker J.R., Chandler C.M., Errazquin Ciudad R., Roohollahi K., Fritzke M., Hoskins E.E., Jonlin E.C., Wakefield L., Sullivan L.B., Chen E.Y., Dorsman J.C., Brakenhoff R.H., Paulovich A.G., Grompe M., Garcia-Escudero R., Wells S.I., Smogorzewska A., Monnat R.J. Jr.
Fanconi anemia-isogenic head and neck cancer cell line pairs: a basic and translational science resource.
Int. J. Cancer 153:183-196(2023)