ID   VU-SCC-094
AC   CVCL_XX17
SY   VU-SCC-94; 93VU094
DR   Wikidata; Q98134583
RX   PubMed=15735012;
RX   PubMed=23613873;
RX   PubMed=26122845;
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; c.919+1G>A (IVS8+1G>A); ClinVar=VCV000633606; Zygosity=Unspecified; Note=Splice donor mutation (PubMed=15735012; PubMed=23613873).
DI   NCIt; C4648; Tongue squamous cell carcinoma
DI   ORDO; Orphanet_457252; Squamous cell carcinoma of the oral tongue
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   65Y
CA   Cancer cell line
DT   Created: 19-12-19; Last updated: 19-12-24; Version: 8
//
RX   PubMed=15735012; DOI=10.1158/0008-5472.CAN-04-3665;
RA   van Zeeburg H.J.T., Snijders P.J.F., Pals G., Hermsen M.A.J.A.,
RA   Rooimans M.A., Bagby G., Soulier J., Gluckman E., Wennerberg J.,
RA   Leemans C.R., Joenje H., Brakenhoff R.H.;
RT   "Generation and molecular characterization of head and neck squamous
RT   cell lines of Fanconi anemia patients.";
RL   Cancer Res. 65:1271-1276(2005).
//
RX   PubMed=23613873; DOI=10.1371/journal.pone.0061555; PMCID=PMC3629194;
RA   Martens-de Kemp S.R., Dalm S.U., Wijnolts F.M.J., Brink A.,
RA   Honeywell R.J., Peters G.J., Braakhuis B.J.M., Brakenhoff R.H.;
RT   "DNA-bound platinum is the major determinant of cisplatin sensitivity
RT   in head and neck squamous carcinoma cells.";
RL   PLoS ONE 8:E61555-E61555(2013).
//
RX   PubMed=26122845; DOI=10.1158/0008-5472.CAN-15-0528;
RA   Stoepker C., Ameziane N., van der Lelij P., Kooi I.E., Oostra A.B.,
RA   Rooimans M.A., van Mil S.E., Brink A., Dietrich R., Balk J.A.,
RA   Ylstra B., Joenje H., Feller S.M., Brakenhoff R.H.;
RT   "Defects in the Fanconi anemia pathway and chromatid cohesion in head
RT   and neck cancer.";
RL   Cancer Res. 75:3543-3553(2015).
//