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Cellosaurus 7SuR (CVCL_XI63)

[Text version]
Cell line name 7SuR
Accession CVCL_XI63
Resource Identification Initiative To cite this cell line use: 7SuR (RRID:CVCL_XI63)
Comments Group: Patented cell line.
Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C2014217.
Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_38940; Sunitinib.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Sequence variations
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Gln149Ter (c.445C>T); ClinVar=VCV000404164; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; c.560-2A>G; ClinVar=VCV003148158; Zygosity=Heterozygous; Note=Splice acceptor mutation (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro278Ala (c.832C>G); ClinVar=VCV000376645; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:12687; VHL; Simple; p.Gly104Alafs*55 (c.311delG); Zygosity=Homozygous (from parent cell line).
Disease Renal cell carcinoma (NCIt: C9385)
Renal cell carcinoma (ORDO: Orphanet_217071)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1051 (786-O)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Publications

Patent=CN104988122B
Qu L., Wang L.-H., Liu B., Chen C., Wu Z.-J., Zhang W.
Renal cancer sunitinib drug-resistant cell system and establishment method thereof.
Patent number CN104988122B, 21-Sep-2018

Cross-references
Cell line databases/resources cancercelllines; CVCL_XI63
CCRID; 4201PAT-CCTCC00547
Encyclopedic resources Wikidata; Q93310157
Entry history
Entry creation19-Dec-2019
Last entry update19-Dec-2024
Version number11