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Cellosaurus 44As3 (CVCL_XG62)

[Text version]
Cell line name 44As3
Accession CVCL_XG62
Resource Identification Initiative To cite this cell line use: 44As3 (RRID:CVCL_XG62)
Comments Population: Japanese.
Characteristics: Highly metastatic. Strong capability of inducing the formation of ascites.
Characteristics: Parent cell line was injected subcutaneously into BALB/c nude mice. Cells from metastatic ascitic tumor cells were harvested and re-injected into mice. This process was carried out 12 times.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Disease Gastric signet ring cell adenocarcinoma (NCIt: C5250)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A388 (HSC-44PE)
Children:
CVCL_C7UQ (44As3Luc)
Sex of cell Female
Age at sampling 28Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1888

Markers:
AmelogeninX
CSF1PO11,12
D5S81810
D7S82011
D13S3178
D16S53913
TH018,9
TPOX8
vWA17

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Publications

PubMed=15958054; DOI=10.1111/j.1349-7006.2005.00054.x; PMCID=PMC11158165
Yanagihara K., Takigahira M., Tanaka H., Komatsu T., Fukumoto H., Koizumi F., Nishio K., Ochiya T., Ino Y., Hirohashi S.
Development and biological analysis of peritoneal metastasis mouse models for human scirrhous stomach cancer.
Cancer Sci. 96:323-332(2005)

PubMed=19010905; DOI=10.1158/0008-5472.CAN-08-2822
Nakajima T.E., Yanagihara K., Takigahira M., Yasunaga M., Kato K., Hamaguchi T., Yamada Y., Shimada Y., Mihara K., Ochiya T., Matsumura Y.
Antitumor effect of SN-38-releasing polymeric micelles, NK012, on spontaneous peritoneal metastases from orthotopic gastric cancer in mice compared with irinotecan.
Cancer Res. 68:9318-9322(2008)

PubMed=26934957; DOI=10.1038/srep22371; PMCID=PMC4776110
Kurashige J., Hasegawa T., Niida A., Sugimachi K., Deng N., Mima K., Uchi R., Sawada G., Takahashi Y., Eguchi H., Inomata M., Kitano S., Fukagawa T., Sasako M., Sasaki H., Sasaki S., Mori M., Yanagihara K., Baba H., Miyano S., Tan P., Mimori K.
Integrated molecular profiling of human gastric cancer identifies DDR2 as a potential regulator of peritoneal dissemination.
Sci. Rep. 6:22371-22371(2016)

Cross-references
Cell line collections (Providers) JCRB; JCRB1888
Encyclopedic resources Wikidata; Q93307015
Entry history
Entry creation06-Sep-2019
Last entry update02-May-2024
Version number6