ID   PH2MT
AC   CVCL_XG27
DR   Wikidata; Q98128570
RX   PubMed=11888918;
RX   PubMed=15705902;
CC   Characteristics: Derived from a tumor formed in athymic mice by injection of the parent cell line.
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P01110; Avian myelocytomatosis virus MC29 v-Myc.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: v-Myc.
CC   Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
CC   Cell type: Fibroblast of foreskin; CL=CL_1001608.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_XG25 ! MSU-1.1-T24 2
SX   Male
AG   <1M
CA   Transformed cell line
DT   Created: 06-09-19; Last updated: 19-12-24; Version: 8
//
RX   PubMed=11888918;
RA   Havre P.A., O'Reilly S., McCormick J.J., Brash D.E.;
RT   "Transformed and tumor-derived human cells exhibit preferential
RT   sensitivity to the thiol antioxidants, N-acetyl cysteine and
RT   penicillamine.";
RL   Cancer Res. 62:1443-1449(2002).
//
RX   PubMed=15705902;
RA   Lou Z.-J., O'Reilly S., Liang H.-Y., Maher V.M., Sleight S.D.,
RA   McCormick J.J.;
RT   "Down-regulation of overexpressed Sp1 protein in human fibrosarcoma
RT   cell lines inhibits tumor formation.";
RL   Cancer Res. 65:1007-1017(2005).
//