ID   MCF7-Cas9-542
AC   CVCL_XD68
DR   cancercelllines; CVCL_XD68
DR   CCRID; 1101HUM-PUMC000542
DR   Wikidata; Q95986786
CC   Population: Caucasian.
CC   Characteristics: Transduced with a Cas9-Flag-Neo construct.
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
ST   Source(s): CCRID=1101HUM-PUMC000542
ST   Amelogenin: X
ST   CSF1PO: 10
ST   D12S391: 18,20
ST   D13S317: 11
ST   D16S539: 11,12
ST   D18S51: 14
ST   D19S433: 13,14
ST   D21S11: 30
ST   D2S1338: 21,23
ST   D3S1358: 16
ST   D5S818: 11,12
ST   D6S1043: 12,18
ST   D7S820: 8,9
ST   D8S1179: 10,14
ST   FGA: 23,24,25
ST   Penta E: 7,12
ST   TH01: 6
ST   TPOX: 9,12
ST   vWA: 14,15
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0031 ! MCF-7
SX   Female
AG   69Y
CA   Cancer cell line
DT   Created: 06-09-19; Last updated: 10-09-24; Version: 11
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