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Cellosaurus HepG2-Luc2-tdT (CVCL_XD61)

[Text version]
Cell line name HepG2-Luc2-tdT
Accession CVCL_XD61
Resource Identification Initiative To cite this cell line use: HepG2-Luc2-tdT (RRID:CVCL_XD61)
Comments Population: Caucasian.
Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Firefly luciferase (Note=With optimized codon usage for mammalian expression).
Genetic integration: Method=Transfection; Gene=FPbase; PGG5S; tdTomato (Note=Bright red fluorescent protein derived from drFP583 (DsRed)).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Cross-references
Cell line databases/resources cancercelllines; CVCL_XD61
CCRID; 1101HUM-PUMC000802
Encyclopedic resources Wikidata; Q94103474
Entry history
Entry creation06-Sep-2019
Last entry update19-Dec-2024
Version number13