Cellosaurus cell line H2030-TGL (CVCL

Cellosaurus H2030-TGL (CVCL_XA21)

[Text version]

Cell line name

H2030-TGL

Accession

CVCL_XA21

Resource Identification Initiative

To cite this cell line use: H2030-TGL (RRID:CVCL_XA21)

Comments

Population: Caucasian.
Characteristics: Transfected with HSV1-TK/GFP/Fluc (TGL).
Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; Q9QNF7; Human herpesvirus 1 TK.
Omics: Transcriptome analysis by microarray.
Caution: In PubMed=19576624 and the associated GEO data sets H2030-TGL is termed H2030 Parental.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.

Sequence variations

Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly262Val (c.785G>T); ClinVar=VCV000428889; Zygosity=Homozygous (from parent cell line).

Disease

Lung adenocarcinoma (NCIt: C3512)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_1517 (NCI-H2030)
Children:

CVCL_XA22 (H2030-BrM3)

Sex of cell

Male

Age at sampling

Age unspecified