ID   OV-MZ-2a
AC   CVCL_X955
DR   cancercelllines; CVCL_X955
DR   Wikidata; Q54936850
RX   PubMed=10741907;
RX   PubMed=11242531;
RX   PubMed=15153938;
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Unspecified (PubMed=15153938).
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
DI   NCIt; C7978; Ovarian serous cystadenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_X951 ! OV-MZ-2
SX   Female
AG   55Y
CA   Cancer cell line
DT   Created: 05-09-14; Last updated: 19-12-24; Version: 9
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RX   PubMed=10741907; DOI=10.1007/s004320050023;
RA   Wu Q., Kreienberg R., Runnebaum I.B.;
RT   "Growth suppression of human ovarian carcinoma OV-MZ-2a and OV-MZ-32
RT   cells mediated by gene transfer of wild-type p53 enhanced by
RT   chemotherapy in vitro.";
RL   J. Cancer Res. Clin. Oncol. 126:139-144(2000).
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RX   PubMed=11242531; DOI=10.1089/10430340150504019;
RA   Bruning A., Kohler T., Quist S.R., Wang-Gohrke S., Mobus V.J.,
RA   Kreienberg R., Runnebaum I.B.;
RT   "Adenoviral transduction efficiency of ovarian cancer cells can be
RT   limited by loss of integrin beta3 subunit expression and increased by
RT   reconstitution of integrin alphaVbeta3.";
RL   Hum. Gene Ther. 12:391-399(2001).
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RX   PubMed=15153938; DOI=10.1038/sj.cgt.7700727;
RA   Quist S.R., Wang-Gohrke S., Kohler T., Kreienberg R., Runnebaum I.B.;
RT   "Cooperative effect of adenoviral p53 gene therapy and standard
RT   chemotherapy in ovarian cancer cells independent of the endogenous p53
RT   status.";
RL   Cancer Gene Ther. 11:547-554(2004).
//