Cellosaurus cell line CML-C-1 (CVCL

Cellosaurus CML-C-1 (CVCL_X930)

Cross-references
Cell line name	CML-C-1
Accession	CVCL_X930
Resource Identification Initiative	To cite this cell line use: CML-C-1 (RRID:CVCL_X930)
Comments	Population: Japanese. Characteristics: Dependent on mouse bone marrow stromal cells for growth. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations	Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (PubMed=7540608; PubMed=10071072).
Disease	Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174) Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	42Y
Category	Cancer cell line
Publications	PubMed=7540608; DOI=10.1111/j.1349-7006.1995.tb03078.x; PMCID=PMC5920846 Kubonishi I., Takeuchi S., Uemura Y., Kamioka M., Asahi Y., Ohtsuki Y., Miyoshi I. Direct transplantation of chronic myelogenous leukemia cells into nude mice and establishment of a leukemic stem cell (Ph1+, CD34+) line dependent on mouse bone marrow stromal cells in vitro. Jpn. J. Cancer Res. 86:451-459(1995) PubMed=10071072; DOI=10.1016/S0145-2126(98)00171-4 Drexler H.G., MacLeod R.A.F., Uphoff C.C. Leukemia cell lines: in vitro models for the study of Philadelphia chromosome-positive leukemia. Leuk. Res. 23:207-215(1999) DOI=10.1016/B978-0-12-221970-2.50457-5 Drexler H.G. The leukemia-lymphoma cell line factsbook. (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)
Encyclopedic resources	Wikidata; Q54813801
Entry history
Entry creation	05-Sep-2014
Last entry update	19-Dec-2024
Version number	13