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Cellosaurus TK-6 [Human leukemia] (CVCL_X907)

[Text version]
Cell line name TK-6 [Human leukemia]
Synonyms TK6
Accession CVCL_X907
Resource Identification Initiative To cite this cell line use: TK-6 [Human leukemia] (RRID:CVCL_X907)
Comments Part of: LL-100 blood cancer cell line panel.
Population: Japanese.
Doubling time: ~60-72 hours (DSMZ=ACC-723).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
HLA typing Source: DSMZCellDive=ACC-723
Class I
HLA-AA*02:06:01,33:03:01
HLA-BB*40:02:01,44:03:01
HLA-CC*03:04:01;14:03
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 30Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-723

Markers:
AmelogeninX,Y
CSF1PO10,11
D2S133819,24
D3S135815
D5S81811,12
D7S8208,11
D8S117912,14
D13S3178,13
D16S5399,12
D18S5112,14
D19S43313,14
D21S1129,32.2
FGA23,25
Penta D11,12
Penta E10,19
TH016,9
TPOX8
vWA15,16

Run an STR similarity search on this cell line
Publications

PubMed=7475285
Watanabe T., Kataoka T., Mizuta S., Kobayashi M., Uchida T., Imai K., Wada H., Kinoshita T., Murate T., Mizutani S., Saito H., Hotta T.
Establishment and characterization of a novel cell line, TK-6, derived from T cell blast crisis of chronic myelogenous leukemia, with the secretion of parathyroid hormone-related protein.
Leukemia 9:1926-1934(1995)

PubMed=9737692; DOI=10.1038/sj.leu.2401113
Tomita A., Watanabe T., Kosugi H., Ohashi H., Uchida T., Kinoshita T., Mizutani S., Hotta T., Murate T., Seto M., Saito H.
Truncated c-Myb expression in the human leukemia cell line TK-6.
Leukemia 12:1422-1429(1998)

PubMed=10071072; DOI=10.1016/S0145-2126(98)00171-4
Drexler H.G., MacLeod R.A.F., Uphoff C.C.
Leukemia cell lines: in vitro models for the study of Philadelphia chromosome-positive leukemia.
Leuk. Res. 23:207-215(1999)

PubMed=10576511; DOI=10.1016/S0145-2126(99)00131-9
Uphoff C.C., Habig S., Fombonne S., Matsuo Y., Drexler H.G.
ABL-BCR expression in BCR-ABL-positive human leukemia cell lines.
Leuk. Res. 23:1055-1060(1999)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=31160637; DOI=10.1038/s41598-019-44491-x; PMCID=PMC6547646
Quentmeier H., Pommerenke C., Dirks W.G., Eberth S., Koeppel M., MacLeod R.A.F., Nagel S., Steube K.G., Uphoff C.C., Drexler H.G.
The LL-100 panel: 100 cell lines for blood cancer studies.
Sci. Rep. 9:8218-8218(2019)

Cross-references
Cell line collections (Providers) DSMZ; ACC-723
Cell line databases/resources CGH-DB; 9213-4
DSMZCellDive; ACC-723
Biological sample resources BioSample; SAMN03473400
Encyclopedic resources Wikidata; Q54972529
Gene expression databases ArrayExpress; E-MTAB-7721
ArrayExpress; E-MTAB-7722
Polymorphism and mutation databases Cosmic; 1483366
Entry history
Entry creation05-Sep-2014
Last entry update19-Dec-2024
Version number19