ID   HH4
AC   CVCL_X906
DR   Wikidata; Q54887478
RX   Patent=US4302535;
RX   PubMed=214074;
RX   PubMed=6810168;
CC   Population: Caucasian.
CC   Characteristics: Compared to the parent cell line, does not require a feeder layer in order to form colonies in soft agarose.
CC   Sequence variation: Mutation; HGNC; 11272; SPTA1; Simple; p.Ser1163Ala (c.3487T>G); ClinVar=VCV000258929; Zygosity=Homozygous (from parent cell line).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Derived from site: In situ; Spleen; UBERON=UBERON_0002106.
DI   NCIt; C97074; Hereditary spherocytosis
DI   ORDO; Orphanet_822; Hereditary spherocytosis
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_6544 ! WIL2
SX   Male
AG   5Y
CA   Transformed cell line
DT   Created: 05-09-14; Last updated: 29-06-23; Version: 11
//
RX   Patent=US4302535;
RA   Skopek T.R., Liber H.L., Penman B.W., Thilly W.G., Hoppe H. 4th;
RT   "Assay for mutagenesis in heterozygous diploid human lymphoblasts.";
RL   Patent number US4302535, 24-Nov-1981.
//
RX   PubMed=214074; DOI=10.1016/0006-291X(78)90185-7;
RA   Skopek T.R., Liber H.L., Penman B.W., Thilly W.G.;
RT   "Isolation of a human lymphoblastoid line heterozygous at the
RT   thymidine kinase locus: possibility for a rapid human cell mutation
RT   assay.";
RL   Biochem. Biophys. Res. Commun. 84:411-416(1978).
//
RX   PubMed=6810168; DOI=10.1016/0027-5107(82)90308-6;
RA   Liber H.L., Thilly W.G.;
RT   "Mutation assay at the thymidine kinase locus in diploid human
RT   lymphoblasts.";
RL   Mutat. Res. 94:467-485(1982).
//