Cell line name |
Jurkat-tat |
Accession |
CVCL_X692 |
Resource Identification Initiative |
To cite this cell line use: Jurkat-tat (RRID:CVCL_X692) |
Comments |
Group: Patented cell line. Population: Caucasian. Doubling time: 25 hours (BEI_Resources=ARP-1399). Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. Cell type: T-cell; CL=CL_0000084. |
Sequence variations |
- Mutation; HGNC; HGNC:959; BAX; Simple; p.Glu41Argfs*19 (c.121delG); ClinVar=VCV000009512; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:959; BAX; Simple; p.Glu41Glyfs*33 (c.121dupG); ClinVar=VCV000009511; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.Arg505Cys (c.1513C>T); ClinVar=VCV000069961; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:6079; INPP5D; Simple; p.Gln345Ter (c.1033C>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:6079; INPP5D; Simple; c.1097+1065_1097+1112del47; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:7325; MSH2; Simple; p.Arg711Ter (c.2131C>T); ClinVar=VCV000090903; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:7329; MSH6; Simple; p.Phe1088Serfs*2 (c.3261delC); ClinVar=VCV000089363; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Heterozygous (from parent cell line).
|
Disease |
Childhood T acute lymphoblastic leukemia (NCIt: C7953) Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_0065 (Jurkat) |
Sex of cell |
Male |
Age at sampling |
14Y |
Category |
Cancer cell line |
Publications | PubMed=2156043 Caputo A., Sodroski J.G., Haseltine W.A. Constitutive expression of HIV-1 tat protein in human Jurkat T cells using a BK virus vector. J. Acquir. Immune Defic. Syndr. 3:372-379(1990) Patent=US4981790 Haseltine W.A., Rosen C.A., Sodroski J.G., Goh W.C. Stable tatIII cell lines, tatIII gene products, and assay methods. Patent number US4981790, 01-Jan-1991 |
Cross-references |
Cell line collections (Providers) |
BEI_Resources; ARP-1399
|
Cell line databases/resources |
cancercelllines; CVCL_X692
|
Encyclopedic resources |
Wikidata; Q54899162
|
Entry history |
Entry creation | 05-Sep-2014 |
Last entry update | 19-Dec-2024 |
Version number | 19 |
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