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Cellosaurus ClearCa-5 (CVCL_X574)

[Text version]
Cell line name ClearCa-5
Synonyms clearCa-5
Accession CVCL_X574
Resource Identification Initiative To cite this cell line use: ClearCa-5 (RRID:CVCL_X574)
Comments Doubling time: 32 hours (PubMed=9146668).
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; c.952_966del15; Zygosity=Unspecified (PubMed=15863265).
Disease Clear cell renal cell carcinoma (NCIt: C4033)
Clear cell renal carcinoma (ORDO: Orphanet_319276)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=9146668; DOI=10.1016/S0022-5347(01)64778-5
Ramp U., Jaquet K., Reinecke P., Schardt C., Friebe-Hoffmann U., Nitsch T., Marx N., Gabbert H.E., Gerharz C.-D.
Functional intactness of stimulatory and inhibitory autocrine loops in human renal carcinoma cell lines of the clear cell type.
J. Urol. 157:2345-2350(1997)

PubMed=10737390; DOI=10.1054/bjoc.1999.1043; PMCID=PMC2374431
Engers R., Mrzyk S., Springer E., Fabbro D., Weissgerber G., Gerharz C.-D., Gabbert H.E.
Protein kinase C in human renal cell carcinomas: role in invasion and differential isoenzyme expression.
Br. J. Cancer 82:1063-1069(2000)

PubMed=11139287; DOI=10.1038/sj.cdd.4400746
Dejosez M., Ramp U., Mahotka C., Krieg A., Walczak H., Gabbert H.E., Gerharz C.-D.
Sensitivity to TRAIL/APO-2L-mediated apoptosis in human renal cell carcinomas and its enhancement by topotecan.
Cell Death Differ. 7:1127-1136(2000)

CLPUB00411
Petek O.
Analysis of expression and mutation of the antimetastatic gene NM23 in human renal carcinoma cell lines and epithelioid sarcomas.
Thesis MD (2002); Heinrich-Heine-Universitat Dusseldorf; Dusseldorf; Germany

CLPUB00407
Krieg A.
Characterization and functional analysis of the TRAIL system and the inhibitor of apoptosis protein (IAP) family in human neoplasia.
Thesis MD (2005); Heinrich-Heine-Universitat Dusseldorf; Dusseldorf; Germany

PubMed=15863265; DOI=10.1016/j.canlet.2004.09.045
Reinecke P., Kalinski T., Mahotka C., Schmitz M., Dejosez M., Gabbert H.E., Gerharz C.-D.
Paclitaxel/taxol sensitivity in human renal cell carcinoma is not determined by the p53 status.
Cancer Lett. 222:165-171(2005)

Cross-references
Encyclopedic resources Wikidata; Q54813625
Polymorphism and mutation databases IARC_TP53; 23210
Entry history
Entry creation05-Sep-2014
Last entry update19-Dec-2024
Version number9