ID   273T
AC   CVCL_X482
DR   cancercelllines; CVCL_X482
DR   Cosmic; 910551
DR   GEO; GSM784285
DR   GEO; GSM827491
DR   Progenetix; CVCL_X482
DR   Wikidata; Q54583760
RX   PubMed=10545285;
RX   PubMed=15735034;
RX   PubMed=20215515;
CC   From: Siegfried, Jill M.; University of Pittsburgh; Pittsburgh; USA.
CC   Sequence variation: Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Tyr727Cys (c.2180A>G); dbSNP=rs138240620; Zygosity=Unspecified (PubMed=15735034).
CC   Omics: SNP array analysis.
CC   Miscellaneous: Age of donor from personal communication of Siegfried, Jill M.
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
DI   NCIt; C3493; Lung squamous cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   88Y
CA   Cancer cell line
DT   Created: 05-09-14; Last updated: 19-12-24; Version: 14
//
RX   PubMed=10545285; DOI=10.1006/pupt.1999.0210;
RA   Siegfried J.M., Krishnamachary N., Gaither Davis A.L., Gubish C.T.,
RA   Hunt J.D., Shriver S.P.;
RT   "Evidence for autocrine actions of neuromedin B and gastrin-releasing
RT   peptide in non-small cell lung cancer.";
RL   Pulm. Pharmacol. Ther. 12:291-302(1999).
//
RX   PubMed=15735034; DOI=10.1158/0008-5472.CAN-04-1872;
RA   Stabile L.P., Lyker J.S., Gubish C.T., Zhang W.-P., Grandis J.R.,
RA   Siegfried J.M.;
RT   "Combined targeting of the estrogen receptor and the epidermal growth
RT   factor receptor in non-small cell lung cancer shows enhanced
RT   antiproliferative effects.";
RL   Cancer Res. 65:1459-1470(2005).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662;
RA   Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P.,
RA   Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J.,
RA   Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C.,
RA   Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J.,
RA   Haber D.A.;
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//