Cellosaurus logo
expasy logo

Cellosaurus MMH-D3 (CVCL_X374)

[Text version]
Cell line name MMH-D3
Synonyms MMH D3; D3; Met Murine Hepatocytes-D3
Accession CVCL_X374
Resource Identification Initiative To cite this cell line use: MMH-D3 (RRID:CVCL_X374)
Comments Genetic integration: Method=Transgenic mouse; Gene=HGNC; HGNC:7029; MET (Note=With p.Met1_Leu955del = cyto-Met).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Cell type: Hepatocyte; CL=CL_0000182.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Sex of cell Sex unspecified
Age at sampling 3D
Category Spontaneously immortalized cell line
Web pages Info; COPE; -; http://www.cells-talk.com/index.php/page/copelibrary?key=MMH-D3
Publications

PubMed=9034332; DOI=10.1093/emboj/16.3.495; PMCID=PMC1169653
Amicone L., Spagnoli F.M., Spath G.F., Giordano S., Tommasini C., Bernardini S., De Luca V., Della Rocca C., Weiss M.C., Comoglio P.M., Tripodi M.
Transgenic expression in the liver of truncated Met blocks apoptosis and permits immortalization of hepatocytes.
EMBO J. 16:495-503(1997)

PubMed=9817765; DOI=10.1083/jcb.143.4.1101; PMCID=PMC2132947
Spagnoli F.M., Amicone L., Tripodi M., Weiss M.C.
Identification of a bipotential precursor cell in hepatic cell lines derived from transgenic mice expressing cyto-Met in the liver.
J. Cell Biol. 143:1101-1112(1998)

PubMed=9828230; DOI=10.1002/hep.510280626
Aiuti A., Cicchini C., Bernardini S., Fedele G., Amicone L., Fantoni A., Tripodi M.
Hematopoietic support and cytokine expression of murine-stable hepatocyte cell lines (MMH).
Hepatology 28:1645-1654(1998)

PubMed=10457350; DOI=10.1002/(SICI)1097-4652(199910)181:1<24::AID-JCP3>3.0.CO;2-0
Bellovino D., Lanyau-Dominguez Y., Garaguso I., Amicone L., Cavallari C., Tripodi M., Gaetani S.
MMH cells: an in vitro model for the study of retinol-binding protein secretion regulated by retinol.
J. Cell. Physiol. 181:24-32(1999)

Cross-references
Encyclopedic resources Wikidata; Q54906224
Entry history
Entry creation17-Jul-2014
Last entry update10-Apr-2025
Version number9