Cellosaurus cell line H4AzC2 (CVCL

Cross-references
Cell line name	H4AzC2
Accession	CVCL_X358
Resource Identification Initiative	To cite this cell line use: H4AzC2 (RRID:CVCL_X358)
Comments	Selected for resistance to: ChEBI; CHEBI:63486; 8-azaguanine. Transformant: ChEBI; CHEBI:23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE). Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease	Rat hepatocellular carcinoma (NCIt: C60416)
Species of origin	Rattus norvegicus (Rat) (NCBI Taxonomy: 10116) Breed/subspecies: AxC; RS=RS:0000369.
Originate from same individual	CVCL_4623 ! H4-II
Sex of cell	Male
Category	Cancer cell line
Publications	PubMed=28957; DOI=10.1016/0014-4827(78)90280-X Leinwand L.A., Strair R.K., Ruddle F.H. Phenotypic and molecular expression of albumin in rat hepatoma x L cell hybrids. Exp. Cell Res. 115:261-268(1978) PubMed=203590; DOI=10.1016/S0021-9258(17)34868-8 Strair R.K., Yap S.H., Nadal-Ginard B., Shafritz D.A. Identification of a high molecular weight presumptive precursor to albumin mRNA in the nucleus of rat liver and hepatoma cell line H4AZC2. J. Biol. Chem. 253:1328-1331(1978) PubMed=9745712; DOI=10.1111/j.1432-0436.1998.00215.x Zvibel I., Fiorino A.S., Brill S., Reid L.M. Phenotypic characterization of rat hepatoma cell lines and lineage-specific regulation of gene expression by differentiation agents. Differentiation 63:215-223(1998)
Encyclopedic resources	Wikidata; Q54872155
Entry history
Entry creation	17-Jul-2014
Last entry update	10-Sep-2024
Version number	8