ID   NP460hTert
AC   CVCL_X205
SY   NP460 hTert; NP460
DR   Wikidata; Q54930966
RX   DOI=10.1016/B978-0-12-814936-2.00005-5;
RX   PubMed=16688717;
RX   PubMed=18196576;
RX   PubMed=23161911;
CC   Population: Chinese.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Pharynx, nasopharynx, epithelium; UBERON=UBERON_0001951.
ST   Source(s): PubMed=18196576
ST   Amelogenin: X,Y
ST   CSF1PO: 13,14
ST   D13S317: 9,10
ST   D16S539: 11,12
ST   D18S51: 13,21
ST   D19S433: 15,15.2
ST   D21S11: 29,32.2
ST   D2S1338: 20,21
ST   D3S1358: 15,16
ST   D5S818: 11,12
ST   D7S820: 10,11
ST   D8S1179: 13,14
ST   FGA: 22,25
ST   TH01: 7,10
ST   TPOX: 9,11
ST   vWA: 17,19
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   46Y
CA   Telomerase immortalized cell line
DT   Created: 17-07-14; Last updated: 19-12-24; Version: 9
//
RX   DOI=10.1016/B978-0-12-814936-2.00005-5;
RA   Yip Y.-L., Lin W.-T., Deng W., Tsang C.-M., Tsao S.-W.;
RT   "Establishment of nasopharyngeal carcinoma cell lines, patient-derived
RT   xenografts, and immortalized nasopharyngeal epithelial cell lines for
RT   nasopharyngeal carcinoma and Epstein-Barr virus infection studies.";
RL   (In book chapter) Nasopharyngeal carcinoma. From etiology to clinical practice; Lee A.W.-M., Lung M.L., Ng W.T. (eds.); pp.85-107; Academic Press; New York; USA (2019).
//
RX   PubMed=16688717; DOI=10.1002/ijc.22032;
RA   Li H.-M., Man C., Jin Y.-S., Deng W., Yip Y.-L., Feng H.-C., Cheung Y.-C.,
RA   Lo K.-W., Meltzer P.S., Wu Z.G., Kwong Y.L., Yuen A.P.-W., Tsao S.-W.;
RT   "Molecular and cytogenetic changes involved in the immortalization of
RT   nasopharyngeal epithelial cells by telomerase.";
RL   Int. J. Cancer 119:1567-1576(2006).
//
RX   PubMed=18196576; DOI=10.1002/ijc.23374;
RA   Chan S.Y.-Y., Choy K.-W., Tsao S.-W., Tao Q., Tang T., Chung G.T.-Y.,
RA   Lo K.-W.;
RT   "Authentication of nasopharyngeal carcinoma tumor lines.";
RL   Int. J. Cancer 122:2169-2171(2008).
//
RX   PubMed=23161911; DOI=10.1073/pnas.1202637109; PMCID=PMC3528537;
RA   Tsang C.-M., Yip Y.-L., Lo K.-W., Deng W., To K.-F., Hau P.-M.,
RA   Lau V.M.-Y., Takada K., Lui V.W.-Y., Lung M.L., Chen H.-L., Zeng M.-S.,
RA   Middeldorp J.M., Cheung A.L.-M., Tsao S.-W.;
RT   "Cyclin D1 overexpression supports stable EBV infection in
RT   nasopharyngeal epithelial cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:E3473-E3482(2012).
//